High Pressure High Temperature Reactions

Hydrogenation | Carbonylation | Amination
HYDROGENATION

Valeshvar is a leader in high-pressure, high-temperature hydrogenation reactions, a technology crucial for the production of pharma intermediates, chemical building blocks, and specialty chemicals.

Both our pilot and industrial hydrogenators are able to perform reactions at a pressure up to 25 bar and at a temperature up to 200°C.

By leveraging our advanced hydrogenation capabilities, we can support your development and production needs for complex molecules across various chemical sectors.

Our capabilities include:

  • High pressure hydrogenation up to 25 bar
  • High temperature hydrogenation up to 200°C
  • Heterogeneous hydrogenation
  • Homogeneous hydrogenation
  • Reductive amination
  • Catalyst expertise (Ni, Pd, Pt, Rh, Ru…)
CARBONYLATION

Carbonylation reactions (hydroformylation and carbonylation) constitute one of the most powerful tools for C-C bond formation in organic synthesis and represent an outstanding example of the application of homogeneous catalysis on an industrial scale. Carbonylation reactions have the potential to provide clean, atom-efficient routes for the synthesis of molecules with carboxylic acid, aldehyde and amide functional groups. However, catalyst product separation is a major problem for the application of homogeneous catalysts on an industrial scale. Valeshvar has an extensive expertise in handling carbonylation reactions.

  • Heterogeneous carbonylation
  • Homogeneous carbonylation
  • Halocarbonylation of Allylic compounds
  • Amidocarbonylation
  • Cyclohydrocarbonylation
  • Heterocycles by Pd catalysed carbonylation
  • Catalyst expertise (Transition metals, Ni, Pd, Pt, Rh, Ru…)
AMINATION

A Chemical reaction in which an Amino group (-NH2) is introduced into molecule. Examples of amination reaction include the reaction of halogenated compounds with ammonia (high pressure and temperature) and the reduction of nitro compounds and nitriles.

  • Acid Catalysed Hydroaminations
  • Metal Catalysed Hydroaminations
  • Reductive Aminations
  • Electrophilic Aminations